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. 1975 Apr;5(2):103-7.
doi: 10.1111/j.1399-0039.1975.tb00537.x.

Improved HL-A typing of cadaveric renal donors. I. Quantitation of HL-A gene dosage

Improved HL-A typing of cadaveric renal donors. I. Quantitation of HL-A gene dosage

L Dumble et al. Tissue Antigens. 1975 Apr.

Abstract

A quantitative microabsorption technique has been used to determine a gene dosage effect on HL-A. This allows homozygosity or heterozygosity of HL-A antigens to be determined prospectively in cadaver donors of renal allografts where less than four antigens were detected by standard lymphocytotoxicity. This in turn provides more precise matching of donor and recipient.

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