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Comparative Study
. 1975 Jun;28(6):1061-6.

The effect of lysozyme on the complement-dependent bactericidal action of different antibody classes

Comparative Study

The effect of lysozyme on the complement-dependent bactericidal action of different antibody classes

R J Heddle et al. Immunology. 1975 Jun.

Abstract

Preparations of rabbit, dog and sheep IgA, IgA and IgM were examined for their antibacterial effects using a complement-dependent bactericidal assay. IgM and IgG were efficient bactericidal antibodies in the presence of complement; IgA, however, contained negligible activity. Except for sheep IgG no enhancement of bactericidal activity was observed in the presence of added lysozyme.

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