Stages of change for adherence with medication regimens for chronic disease: development and validation of a measure
- PMID: 10945512
- DOI: 10.1016/s0149-2918(00)80058-2
Stages of change for adherence with medication regimens for chronic disease: development and validation of a measure
Abstract
Background: The stages-of-change (SOC) model has been used to explain and predict how behavior change occurs, but it is new as an approach to understanding why patients fail to take their medications as prescribed.
Objective: This study validated a 2-item measure of SOC for adherence with medication regimens in 2 groups of patients prescribed pharmacologic therapy for chronic conditions.
Methods: Two cross-sectional studies of attitudes toward medication adherence included the same measure of SOC for medication adherence. One was a sample of 161 HIV-positive patients in the United States, and the other was an international sample of 731 patients with hypertension. The validity of the measure of SOC for medication adherence was examined in both convenience samples using previously validated self-reported measures of adherence (the Medication Adherence Scale and a measure of adherence from the Medical Outcomes Study), and in the HIV sample using electronic monitoring of adherence behavior in 85 patients.
Results: Construct validity was demonstrated in both samples by associations between SOC and the previously validated measures of adherence (P < 0.001), and predictive validity was supported by significant associations between SOC for medication adherence and electronically monitored medication-taking behavior during the next 30 days (P < 0.03).
Conclusions: Behavior-change theory suggests that stage-tailored communication strategies are more effective than uniform health-promotion messages. Our results provide a foundation for the development of interventions for medication adherence that are tailored to patients' readiness for change. Our validated 2-item measure of SOC for medication adherence can be used to match communication strategies to individual motivation and readiness for adherence with chronic disease medication regimens.
Similar articles
-
Validity of a stage of change instrument in assessing medication adherence in indigent patients with HIV infection.Ann Pharmacother. 2007 Feb;41(2):208-14. doi: 10.1345/aph.1H383. Epub 2007 Jan 9. Ann Pharmacother. 2007. PMID: 17213294 Clinical Trial.
-
Behavior-changing methods for improving adherence to medication.Curr Hypertens Rep. 1999 Dec;1(6):477-81. doi: 10.1007/s11906-996-0019-6. Curr Hypertens Rep. 1999. PMID: 10981109
-
Validation of a New Three-Item Self-Report Measure for Medication Adherence.AIDS Behav. 2016 Nov;20(11):2700-2708. doi: 10.1007/s10461-016-1406-x. AIDS Behav. 2016. PMID: 27098408 Free PMC article.
-
Medication adherence and persistence as the cornerstone of effective antihypertensive therapy.Am J Hypertens. 2006 Nov;19(11):1190-6. doi: 10.1016/j.amjhyper.2006.04.006. Am J Hypertens. 2006. PMID: 17070434 Review.
-
A motivational intervention to improve adherence to treatment of chronic disease.J Am Acad Nurse Pract. 2001 Feb;13(2):61-8. doi: 10.1111/j.1745-7599.2001.tb00219.x. J Am Acad Nurse Pract. 2001. PMID: 11930399 Review.
Cited by
-
Adherence to treatment of osteoporosis: a need for study.Osteoporos Int. 2007 Oct;18(10):1311-7. doi: 10.1007/s00198-007-0410-4. Epub 2007 Jun 22. Osteoporos Int. 2007. PMID: 17585359 Review.
-
A cluster-randomized controlled trial evaluating the effect of culturally-appropriate hypertension education among Afro-Surinamese and Ghanaian patients in Dutch general practice: study protocol.BMC Health Serv Res. 2009 Oct 22;9:193. doi: 10.1186/1472-6963-9-193. BMC Health Serv Res. 2009. PMID: 19849857 Free PMC article. Clinical Trial.
-
Magnitude and determinants of nonadherence and nonreadiness to highly active antiretroviral therapy among people living with HIV/AIDS in Northwest Ethiopia: a cross-sectional study.AIDS Res Ther. 2010 Jan 14;7:2. doi: 10.1186/1742-6405-7-2. AIDS Res Ther. 2010. PMID: 20180959 Free PMC article.
-
Measurement Tools and Utility of Hair Analysis for Screening Adherence to Antihypertensive Medication.Glob Heart. 2023 Mar 22;18(1):17. doi: 10.5334/gh.1191. eCollection 2023. Glob Heart. 2023. PMID: 36968302 Free PMC article. Review.
-
Readiness: the state of the science (or the lack thereof).Curr HIV/AIDS Rep. 2010 Nov;7(4):245-52. doi: 10.1007/s11904-010-0056-2. Curr HIV/AIDS Rep. 2010. PMID: 20714831 Free PMC article. Review.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Medical