Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1975 Apr;34(2):190-4.
doi: 10.1136/ard.34.2.190.

Feprazone, a new anti-inflammatory agent. Studies of potency and gastrointestinal tolerance

Clinical Trial

Feprazone, a new anti-inflammatory agent. Studies of potency and gastrointestinal tolerance

M R Fletcher et al. Ann Rheum Dis. 1975 Apr.

Abstract

Two studies are reported; a double-blind cross-over trial of feprazone 600 mg daily and aspirin 3.6 g daily in the treatment of rheumatoid arthritis, and an uncontrolled open study of gastrointestinal tolerance in twenty rheumatoid arthritis patients with known intolerance to other drugs. The first study showed that feprazone was significantly superior to aspirin in all the parameters tested. In the second study all twenty patients showed an improvement of their gastrointestinal symptoms, nineteen reporting no symptoms at all when taking the new preparation.

PubMed Disclaimer

References

    1. Am Pract Dig Treat. 1955 Dec;6(12):1865-9 - PubMed
    1. Br Med J. 1960 Sep 17;2(5202):828-30 - PubMed
    1. Ann Rheum Dis. 1959 Mar;18(1):49-51; French transl 51-2; Spanish transl 52-3 - PubMed
    1. Can Med Assoc J. 1958 Oct 15;79(8):634-8 - PubMed
    1. Arzneimittelforschung. 1972 Jan;22(1):Suppl 1a:265-8 - PubMed

MeSH terms