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. 2000 Sep;83(6):725-8.
doi: 10.1054/bjoc.2000.1330.

Serial analysis of gene expression identifies putative metastasis-associated transcripts in colon tumour cell lines

A Parle-McDermott  1 , P McWilliam, O Tighe, D Dunican, D T Croke
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Serial analysis of gene expression identifies putative metastasis-associated transcripts in colon tumour cell lines

A Parle-McDermott et al. Br J Cancer. 2000 Sep.

Abstract

We have used serial analysis of gene expression (SAGE) to identify gene expression differences between a primary colon tumour cell line (SW480) and an isogenic lymph-node metastasis cell line (SW620). Differential expression was confirmed for the following genes: keratin K5, cystatin S, serum amyloid A, the human homologue of yeast ribosomal S28 and the p32 subunit of human pre-mRNA splicing factor SF2. Expression of confirmed differences were also analysed in other metastatic cell lines.

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