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. 1979 Jun;122(6):2598-604.

Accessory cell requirements for the generation of cytolytic T lymphocytes

C T Lutz, F W Fitch
  • PMID: 109533

Accessory cell requirements for the generation of cytolytic T lymphocytes

C T Lutz et al. J Immunol. 1979 Jun.

Abstract

A system is presented that may simplify the study of accessory cell requirements for CTL generation. Cortisone resistant (CR) thymocytes containing alloreactive CTL precursors do not respond to allogeneic tumor cells unless non-T accessory cells are added to culture. In addition, splenic T cells do not respond to allogeneic tumor cells in the absence of non-T accessory cells. These accessory cells share several properties of macrophages.

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