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. 1975 Jul;13(1):72-8.

The primary antibacterial defense mechanism of the bladder

C L Parsons, C Greenspan, S G Mulholland
  • PMID: 1095522

The primary antibacterial defense mechanism of the bladder

C L Parsons et al. Invest Urol. 1975 Jul.

Abstract

We have developed a model in rabbits for quantitatively determining the attachment of microbial organisms to the vesical mucosa. Our data suggest that the bladder has a primary antibacterial defense mechanism that serves to interrupt microbial attachment. This mechanism seems to be secretory, since after destruction with acid, the resistance to microbial binding returns in less than 24 hr.

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