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Review
. 2000 Aug 29;97(18):9827-9.
doi: 10.1073/pnas.97.18.9827.

Amiloride-sensitive sodium channels contribute to the woes of the flu

W B Guggino  1 , S E Guggino
Affiliations
Review

Amiloride-sensitive sodium channels contribute to the woes of the flu

W B Guggino et al. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

Figure 1
Figure 1
Primary cultures of human bronchial epithelium. A cross section of an air–liquid interface human bronchial epithelial cell culture in which perfluorocarbon/OsO4 fixation has preserved the relationships between cells, airway surface liquid, and mucus. At the top, accumulated mucus (M) containing cell debris and added beads (*) overlays a lucent airway surface liquid (ASL) zone surrounding the cilia. Below this, goblet (G) and ciliated (C) cells overlay basal (B) and intermediate (I) cells above the porous membrane culture support (p). As discussed above, precisely regulated periciliary airway surface fluid depth is a critical determinant of mucus flow. Photomicrograph provided by Scott H. Randell.
See this image and copyright information in PMC

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References

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