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Review
. 2000 Sep;7(9):724-9.
doi: 10.1038/78941.

Measuring conformational dynamics of biomolecules by single molecule fluorescence spectroscopy

S Weiss  1
Affiliations
Review

Measuring conformational dynamics of biomolecules by single molecule fluorescence spectroscopy

S Weiss. Nat Struct Biol. 2000 Sep.

Abstract

Dynamic structural changes of macromolecules undergoing biochemical reactions can be studied using novel single molecule spectroscopy tools. Recent advances in applying such distance and orientation molecular rulers to biological systems are reviewed, and future prospects and challenges are discussed.

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