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Editorial

. 2000 Aug;121(2):179-80.

doi: 10.1046/j.1365-2249.2000.01289.x.

Cyclosporin: nephro-protective as well as nephrotoxic?

PMID: 10970156
PMCID: PMC1905685
DOI: 10.1046/j.1365-2249.2000.01289.x

Editorial

Cyclosporin: nephro-protective as well as nephrotoxic?

P W Mathieson. Clin Exp Immunol. 2000 Aug.

. 2000 Aug;121(2):179-80.

doi: 10.1046/j.1365-2249.2000.01289.x.

Author

PMID: 10970156
PMCID: PMC1905685
DOI: 10.1046/j.1365-2249.2000.01289.x

No abstract available

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Comment on

Cyclosporin A reduces expression of adhesion molecules in the kidney of rats with chronic serum sickness.
Rincón J, Parra G, Quiroz Y, Benatuil L, Rodríguez-Iturbe B. Rincón J, et al. Clin Exp Immunol. 2000 Aug;121(2):391-8. doi: 10.1046/j.1365-2249.2000.01251.x. Clin Exp Immunol. 2000. PMID: 10931158 Free PMC article.

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References

1. Calne RY. Pharmacological immunosuppression in clinical organ grafting. Observations on four agents: cyclosporin A, Asta 5122 (cytimun), lambda carrageenan and promethazine hydrochloride. Clin Exp Immunol. 1979;35:1–9. - PMC - PubMed
1. Clipstone NA, Crabtree GR. Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation. Nature. 1992;357:695–7. - PubMed
1. Brazelton TR, Morris RE. Molecular mechanisms of action of new xenobiotic immunosuppressive drugs: tacrolimus (FK506), sirolimus (rapamycin), mycophenolate motetil and leflunomide. Curr Opin Immunol. 1996;8:710–20. - PubMed
1. De Mattos AM, Olyaei AJ, Bennett WM. Nephrotoxicity of immunosuppressive drugs: long-term consequences and challenges for the future. Am J Kidney Dis. 2000;35:333–46. - PubMed
1. Hariharan S, Johnson CP, Bresnahan BA, Taranto SE, McIntosh MJ, Stablein D. Improved graft survival after renal transplantation in the United States, 1998–96. New Engl J Med. 2000;342:605–12. - PubMed

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