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Review
. 2000 Aug;3(4):354-8.
doi: 10.1016/s1369-5274(00)00103-x.

Melanin and virulence in Cryptococcus neoformans

A Casadevall  1 , A L Rosas, J D Nosanchuk
Affiliations
Review

Melanin and virulence in Cryptococcus neoformans

A Casadevall et al. Curr Opin Microbiol. 2000 Aug.

Abstract

Melanin synthesis has been associated with virulence for the human pathogenic fungus Cryptococcus neoformans. Recent evidence indicates that C. neoformans cells synthesize melanin during infection and that this pigment protects the fungus against immune defense mechanisms.

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