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Review
. 2000 Aug;3(4):366-70.
doi: 10.1016/s1369-5274(00)00106-5.

Regulation of host cell translation by viruses and effects on cell function

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Free article
Review

Regulation of host cell translation by viruses and effects on cell function

S R Thompson et al. Curr Opin Microbiol. 2000 Aug.
Free article

Abstract

Viruses have evolved a remarkable variety of strategies to modulate the host cell translation apparatus with the aim of optimizing viral mRNA translation and replication. Recent studies have revealed that modulation of both host and viral mRNA translation can be accomplished by selective alteration of translation factors in virus-infected cells. These findings provide new insights into the functioning of the translational apparatus in both uninfected and infected cells.

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