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• Bacillus subtilis hlpB encodes a conserved stand-alone HNH nuclease-like protein that is essential for viability unless the hlpB deletion is accompanied by the deletion of genes encoding the AddAB DNA repair complex.

  Pediaditakis M, Kaufenstein M, Graumann PL. Pediaditakis M, et al. J Bacteriol. 2012 Nov;194(22):6184-94. doi: 10.1128/JB.05283-11. Epub 2012 Sep 14. J Bacteriol. 2012. PMID: 22984257 Free PMC article.
• The other face of restriction: modification-dependent enzymes.

  Loenen WA, Raleigh EA. Loenen WA, et al. Nucleic Acids Res. 2014 Jan;42(1):56-69. doi: 10.1093/nar/gkt747. Epub 2013 Aug 29. Nucleic Acids Res. 2014. PMID: 23990325 Free PMC article. Review.
• Type II restriction endonuclease R.KpnI is a member of the HNH nuclease superfamily.

  Saravanan M, Bujnicki JM, Cymerman IA, Rao DN, Nagaraja V. Saravanan M, et al. Nucleic Acids Res. 2004 Nov 23;32(20):6129-35. doi: 10.1093/nar/gkh951. Print 2004. Nucleic Acids Res. 2004. PMID: 15562004 Free PMC article.
• Cloning, purification and initial characterization of E. coli McrA, a putative 5-methylcytosine-specific nuclease.

  Mulligan EA, Dunn JJ. Mulligan EA, et al. Protein Expr Purif. 2008 Nov;62(1):98-103. doi: 10.1016/j.pep.2008.06.016. Epub 2008 Jul 10. Protein Expr Purif. 2008. PMID: 18662788 Free PMC article.
• EcoBLMcrX, a classical modification-dependent restriction enzyme in Escherichia coli B: Characterization in vivo and in vitro with a new approach to cleavage site determination.

  Fomenkov A, Sun Z, Dila DK, Anton BP, Roberts RJ, Raleigh EA. Fomenkov A, et al. PLoS One. 2017 Jun 27;12(6):e0179853. doi: 10.1371/journal.pone.0179853. eCollection 2017. PLoS One. 2017. PMID: 28654677 Free PMC article.