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. 2000 Sep;16(9):369-72.
doi: 10.1016/s0168-9525(00)02081-3.

Conserved noncoding sequences are reliable guides to regulatory elements

R C Hardison  1
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Conserved noncoding sequences are reliable guides to regulatory elements

R C Hardison. Trends Genet. 2000 Sep.

Abstract

A 'working draft' of the human genome sequence is now available. Comparisons with the sequences of mouse and other species will be a powerful approach to identifying functional segments of the noncoding regions, such as gene regulatory elements. However, the choice of a species for most effective comparison differs among various loci.

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