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Comparative Study
. 2000 Sep;7(5):842-4.
doi: 10.1128/CDLI.7.5.842-844.2000.

Prevalence of CagA and VacA antibodies in children with Helicobacter pylori-associated peptic ulcer compared to prevalence in pediatric patients with active or nonactive chronic gastritis

T Alarcón  1 , M J Martínez, P Urruzuno, M L Cilleruelo, D Madruga, M Sebastian, D Domingo, J C Sanz, M López-Brea
Affiliations
Comparative Study

Prevalence of CagA and VacA antibodies in children with Helicobacter pylori-associated peptic ulcer compared to prevalence in pediatric patients with active or nonactive chronic gastritis

T Alarcón et al. Clin Diagn Lab Immunol. 2000 Sep.

Abstract

VacA and CagA serological responses were detected in pediatric patients: 44 and 56%, respectively, in peptic ulcer (PU) patients, 33.3 and 44.4% in active chronic gastritis (ACG) patients, and 23.2 and 39.2% in non-ACG patients. Higher seroprevalence to CagA+VacA and to CagA+VacA+35-kDa antigen was found among PU patients. However, a low level of sensitivity and specificity was found for indirect detection of PU patients.

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