Analysis of bacteriophage deoxyribonucleic acid sequences methylated by host- and R-factor-controlled enzymes
- PMID: 1097428
- PMCID: PMC235790
- DOI: 10.1128/jb.123.2.768-770.1975
Analysis of bacteriophage deoxyribonucleic acid sequences methylated by host- and R-factor-controlled enzymes
Abstract
Phages lambda and fd were propagated in Escherichia coli strains that have either host K-12 or the N-3 R-factor deoxyribonucleic acid-cytosine methylase activity. Pyrimidine tracts containing 3H-labeled 5-methylcytosine (MeC) were analyzed; in all cases, the major methylated sequence was 5' ... C-MeC-T ... 3'.
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