Clinical Trial
doi: 10.1016/0030-4220(75)90348-5.
Nystatin and amphotericin B in the treatment of denture-related candidiasis
- PMID: 1097985
- DOI: 10.1016/0030-4220(75)90348-5
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Clinical Trial
Nystatin and amphotericin B in the treatment of denture-related candidiasis
Oral Surg Oral Med Oral Pathol.
1975 Jul.
Abstract
A double-blind trial of nystatin, amphotericin B, and a placebo was carried out in fifty-two cases of denture-related candidiasis and/or angular cheilitis. The drugs effected a significant clinical cure, but recurrence of the signs was common after withdrawal of the drugs. Concurrent bacteriologic examination showed few cures and continued presence of Candida albicans during the trial. A specimen from a red palate was examined histologically.