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. 1975 May;72(5):1887-91.
doi: 10.1073/pnas.72.5.1887.

Single-strand scissions of chromosomal DNA during commitment to recombination at meiosis

G K Jacobson, R Pinon, R E Esposito, M S Esposito

Single-strand scissions of chromosomal DNA during commitment to recombination at meiosis

G K Jacobson et al. Proc Natl Acad Sci U S A. 1975 May.

Abstract

Diploid cells of the yeast Saccharomyces cerevisiae induced to undergo meiosis accumulate single-strand scissions in both template and newly synthesized DNA during commitment to genetic recombination. No evidence for accumulation of double-strand breaks during meiosis was obtained. When commitment to recombination is at the full meiotic level there are approximately 70 to 200 single-strand scissions per meiotic cell in which approximately 150 recombination events have been reported to occur.

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