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Review
. 1999 Apr;1(2):116-22.
doi: 10.1007/s11894-996-0009-5.

Clinical aspects of sphincter of Oddi function and dysfunction

J Toouli  1 , A Craig
Affiliations
Review

Clinical aspects of sphincter of Oddi function and dysfunction

J Toouli et al. Curr Gastroenterol Rep. 1999 Apr.

Abstract

The sphincter of Oddi (SO) functions to regulate the flow of bile and pancreatic juices as well as to prevent the reflux of duodenal contents into the pancreatobiliary system. When dysfunction of the sphincter occurs, symptoms develop relating to either the biliary or pancreatic portions of the sphincter. The mechanism of this dysfunction remains speculative. SO manometry remains the "gold standard" to correctly diagnose the disorder and stratify therapy. Division of the sphincter is effective for SO stenosis, but there is no proven therapy for SO dyskinesia.

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References

    1. Gastrointest Endosc. 1990 Sep-Oct;36(5):458-61 - PubMed
    1. Gastroenterology. 1980 Feb;78(2):317-24 - PubMed
    1. Gastroenterology. 1986 Mar;90(3):728-33 - PubMed
    1. Aust N Z J Med. 1986 Dec;16(6):788-93 - PubMed
    1. Gastroenterology. 1985 May;88(5 Pt 1):1243-50 - PubMed