Review
doi: 10.1016/s0001-2998(75)80014-6.
Radioligand assay in reproductive biology
- PMID: 1098152
- DOI: 10.1016/s0001-2998(75)80014-6
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Review
Radioligand assay in reproductive biology
Semin Nucl Med.
1975 Jul.
Abstract
Radioligand assays have been developed for the principal reproductive steroids and peptide hormones. Specific binding reagents have included antibodies, plasma binders, and intracellular receptors. In each assay, problems of specificity, sensitivity, and nonspecific inhibitors were encountered. Many features of the endocrine physiology in childhood, during puberty, and in adulthood have been characterized. Hormonal evaluations of endocrine disorders of reproduction are characterized on the basis of their characteristic pathophysiologic alterations.
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