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. 1975 May;5(4):234-7.
doi: 10.1111/j.1399-0039.1975.tb01469.x.

The search for a human equivalent of the mouse T-locus - negative results from a study of HL-A types in spina bifida

M Bobrow, J G Bodmer, W F Bodmer, H O McDevitt, J Lorber, P Swift

The search for a human equivalent of the mouse T-locus - negative results from a study of HL-A types in spina bifida

M Bobrow et al. Tissue Antigens. 1975 May.

Abstract

The spina bifida/anencephaly complex in man in some ways resembles the effects of T-locus mutants in the mouse. To test the hypothesis that these entities are genetically related, HL-A typing was performed in families with multiple cases of central nervous system abnormality. No evidence of linkage was found between HL-A type and the congenital malformation.

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