Notch signaling: Fringe really is a glycosyltransferase
- PMID: 10985380
- DOI: 10.1016/s0960-9822(00)00633-3
Notch signaling: Fringe really is a glycosyltransferase
Abstract
Fringe modifies the ligand-selectivity of Notch in ways that are crucial for a number of Notch's developmental functions. Recent results have confirmed the suspicion that Fringe is a glycosyltransferase that works in the Golgi complex by modifying Notch's glycosylation state.
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