Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2000 Sep 21;10(18):R674-7.
doi: 10.1016/s0960-9822(00)00680-1.

Glycoprotein degradation: do sugars hold the key?

L Frigerio  1 , J M Lord
Affiliations
Free article

Glycoprotein degradation: do sugars hold the key?

L Frigerio et al. Curr Biol. .
Free article

Abstract

Secretory glycoproteins that fail to fold or assemble correctly are retained in the endoplasmic reticulum and eventually degraded. Recent evidence shows that trimming of their N-linked oligosaccharide chains plays a key role in targeting glycoproteins for destruction.

PubMed Disclaimer

MeSH terms

LinkOut - more resources