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Review
. 2000 Oct;18(10):412-20.
doi: 10.1016/s0167-7799(00)01485-2.

Poloxamers and poloxamines in nanoparticle engineering and experimental medicine

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Review

Poloxamers and poloxamines in nanoparticle engineering and experimental medicine

S M Moghimi et al. Trends Biotechnol. 2000 Oct.

Abstract

Poloxamers and poloxamine nonionic surfactants have diverse applications in various biomedical fields ranging from drug delivery and medical imaging to management of vascular diseases and disorders. Although this is a progressive, rapidly advancing field in biotechnology, the future will depend on the recognition and rectification of a range of toxicity issues, which have to be addressed but have frequently been ignored until now.

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