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Case Reports
. 2000 Sep;21(8):1466-9.

Granulomatous hypophysitis due to Wegener's granulomatosis

M Goyal  1 , W Kucharczyk, E Keystone
Affiliations
Case Reports

Granulomatous hypophysitis due to Wegener's granulomatosis

M Goyal et al. AJNR Am J Neuroradiol. 2000 Sep.

Abstract

We describe the MR image findings in a case of granulomatous hypophysitis due to Wegner's granulomatosis. A high index suspicion of hypophysitis based on imaging findings allowed successful medical management and helped avoid surgery. The MR imaging features included a thickened stalk, a diffusely and uniformly enlarged gland, a normal size or minimally enlarged sella, and enhancement of the optic chiasm.

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Figures

<sc>fig</sc> 1.
fig 1.
MR images obtained through the pituitary gland show diffuse enlargement of the pituitary gland. The gland shows diffuse heterogeneous enhancement that extends to the optic chiasm (arrow). Also note the presence of mucosal thickening in the bilateral sphenoid sinus. A, T1-weighted coronal (450/15/4 [TR/TE/excitations]) MR image. B, T2-weighted coronal (4000/90/3; echo train length, 8) MR image. C, Contrast-enhanced T1-weighted coronal (450/15/4) MR image. D, Contrast-enhanced T1-weight sagittal (450/15/4) MR image.
<sc>fig</sc> 2.
fig 2.
Follow-up MR examination after 6-week administration of steroids. Contrast-enhanced T1-weighted coronal (450/15/4) MR image shows dramatic resolution in the size of the pituitary gland. No enhancement is seen in the optic chiasm
See this image and copyright information in PMC

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