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Review
. 2000 Oct;91(4):837-55.
doi: 10.1097/00000539-200010000-00014.

Specific genetic diseases at risk for sedation/anesthesia complications

M G Butler  1 , B G Hayes, M M Hathaway, M L Begleiter
Affiliations
Review

Specific genetic diseases at risk for sedation/anesthesia complications

M G Butler et al. Anesth Analg. 2000 Oct.

Abstract

We reviewed of a number of genetic diseases known or at risk for sedation or anesthesia complications. Some of these conditions are relatively common (e.g., Down's syndrome) whereas others are rare or present with multiple congenital anomalies that have an impact on health care delivery. We listed complications, recommended presedation evaluations, and included checklist items to assist the health care provider administering sedation and anesthesia. A better recognition and awareness of risk factors associated with specific genetic diseases should lessen the likelihood of complications during these procedures.

Implications: This article provides a brief description of potential problematic genetic disorders and associated complications that may manifest during sedation or anesthesia. Recommendations for presedation evaluation and checklist items are given that may impact on the delivery of care for these patients.

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