Hydrosalpinx and ART. Salpingectomy prior to IVF can be recommended to a well-defined subgroup of patients
- PMID: 11006175
- DOI: 10.1093/humrep/15.10.2072
Hydrosalpinx and ART. Salpingectomy prior to IVF can be recommended to a well-defined subgroup of patients
Abstract
The result of the Scandinavian multicentre study on salpingectomy prior to IVF has promoted a discussion on whether there is a risk of unnecessary salpingectomies being performed. We agree that physicians have to discriminate carefully between a hydrosalpinx that should be removed and one that is suitable for surgical repair. Tubal endoscopy is the most advanced tool for that purpose, while transvaginal ultrasound is not appropriate in selecting patients to undergo either salpingectomy or salpingostomy. The Scandinavian study showed that patients with hydrosalpinges which are large enough to be visible on ultrasound before ovarian stimulation, benefit from salpingectomy in terms of improved fertility outcome after IVF. The result of the study does not interfere with the management of distal tubal infertility in general, since it was concluded that not every woman with a large hydrosalpinx should undergo salpingectomy. Hydrosalpinges with preserved mucosa may be better treated with reconstructive surgery as primary treatment instead of salpingectomy and IVF. The latter option may, however, be the secondary treatment after failed conception and re-occlusion of the tubes. Unnecessary salpingectomies should, of course, not be performed and they may easily be avoided by appropriate evaluation of the tubal mucosa at laparoscopy before any final decision of salpingectomy is made. We do not see a major conflict: functional surgery to the tubes with healthy mucosa and salpingectomy to the dilated tubes that are visible on ultrasound and have a severely damaged mucosa.
Comment on
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Hydrosalpinx reduces in-vitro fertilization/embryo transfer pregnancy rates.Hum Reprod. 1994 May;9(5):861-3. doi: 10.1093/oxfordjournals.humrep.a138606. Hum Reprod. 1994. PMID: 7929732 Clinical Trial.
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Hydrosalpinges adversely affect markers of endometrial receptivity.Hum Reprod. 1997 Jul;12(7):1393-8. doi: 10.1093/humrep/12.7.1393. Hum Reprod. 1997. PMID: 9262264
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Is hydrosalpinx fluid cytotoxic?Hum Reprod. 1998 Jun;13(6):1620-4. doi: 10.1093/humrep/13.6.1620. Hum Reprod. 1998. PMID: 9688402
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Hydrosalpinx fluid does not adversely affect the normal development of human embryos and implantation in vitro.Hum Reprod. 1998 Oct;13(1O):2921-5. doi: 10.1093/humrep/13.10.2921. Hum Reprod. 1998. PMID: 9804256
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Pregnancy rates after in-vitro fertilization in cases of tubal infertility with and without hydrosalpinx: a meta-analysis of published comparative studies.Hum Reprod. 1999 May;14(5):1243-9. doi: 10.1093/humrep/14.5.1243. Hum Reprod. 1999. PMID: 10325271
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Hydrosalpinx and IVF outcome: a prospective, randomized multicentre trial in Scandinavia on salpingectomy prior to IVF.Hum Reprod. 1999 Nov;14(11):2762-9. doi: 10.1093/humrep/14.11.2762. Hum Reprod. 1999. PMID: 10548619 Clinical Trial.
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Hydrosalpinx and ART: hydrosalpinx--functional surgery or salpingectomy?Hum Reprod. 2000 Jul;15(7):1427-30. doi: 10.1093/humrep/15.7.1427. Hum Reprod. 2000. PMID: 10875845 Review.
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