Mechanisms of chronic rejection
- PMID: 11007353
- DOI: 10.1016/s0952-7915(00)00132-1
Mechanisms of chronic rejection
Abstract
Chronic rejection remains the major obstacle to long-term allograft survival. Detailed understanding of putative etiologic risk factors, both antigen-dependent and -independent, is important for designing effective therapeutic strategies to ameliorate this process. Cell senescence may be an important factor in chronic rejection.
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