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. 2000 Sep 23;356(9235):1081-2.
doi: 10.1016/S0140-6736(00)02737-9.

Duration of viraemia and faecal viral excretion in acute hepatitis E

R Aggarwal, D Kini, S Sofat, S R Naik, K Krawczynski

Duration of viraemia and faecal viral excretion in acute hepatitis E

R Aggarwal et al. Lancet. .

Abstract

Data on duration of viral excretion and viraemia during hepatitis E virus (HEV) infection are limited. We tested serial stool and serum samples from 20 patients with acute hepatitis E for HEV RNA. Faecal excretion and viraemia in these patients were found to be short lived. In 19 patients, all samples obtained after biochemical resolution of hepatitis tested negative; in the remaining patient, HEV RNA was detected in the serum samples but not in stool after biochemical resolution. Long-term persistence of HEV in body fluids of infected individuals seems to be an unlikely reservoir for transmission of HEV.

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