Formal synthesis of (+/-)-dendrobine: use of the amidofuran cycloaddition/rearrangement sequence
- PMID: 11009389
- DOI: 10.1021/ol006444h
Formal synthesis of (+/-)-dendrobine: use of the amidofuran cycloaddition/rearrangement sequence
Abstract
The formal synthesis of the alkaloid (+/-)-dendrobine (4) was accomplished using the IMDAF cycloaddition/rearrangement sequence of a furanyl carbamate. Conversion of the rearranged cycloadduct to Kende's advanced intermediate in eight steps completed the formal synthesis of (+/-)-dendrobine.
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