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Review
. 2000 Jul;86(7):801-10.

[Intercellular integration in the central nervous system]

[Article in Russian]
V A Otellin  1 , N B Saul'skaia
Affiliations
  • PMID: 11011366
Review

[Intercellular integration in the central nervous system]

[Article in Russian]
V A Otellin et al. Ross Fiziol Zh Im I M Sechenova. 2000 Jul.

Abstract

A humoral mechanism of the intercellular communication in the CNS based on diffusion of neuroactive compounds within the brain extracellular space, was studied. The leading role of the volume transmission was shown in the early stage of ontogeny. Structural basis of this mechanism was studied in adult mammals, and the data on extrasynaptic receptors and release of classical neurotransmitters into the extracellular space was reviewed.

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