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Comment
. 2000 Sep 15;289(5486):1857-9.
doi: 10.1126/science.289.5486.1857.

Molecular biology. Cancer fighter's modus operandi revealed

J Marx
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Molecular biology. Cancer fighter's modus operandi revealed

J Marx. Science. .

Abstract

Researchers have deciphered how a promising cancer drug acts like a smart bomb, homing in on only a very narrow range of its potential targets in the cell. The compound, known as STI-571, has shown remarkable success in early clinical trials on patients with chronic myelogenous leukemia. Now, in work reported on page 1938, scientists reveal just how the compound works--information that could aid in the design of similar cancer therapies.

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