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. 1975 Jul;72(7):2506-10.
doi: 10.1073/pnas.72.7.2506.

In vivo and in vitro phosphorylation of DNA-dependent RNA polymerase of Escherichia coli by bacteriophage-T7-induced protein kinase

W Zillig, H Fujiki, W Blum, D Janeković, M Schweiger, H Rahmsdorf, H Ponta, M Hirsch-Kauffmann

In vivo and in vitro phosphorylation of DNA-dependent RNA polymerase of Escherichia coli by bacteriophage-T7-induced protein kinase

W Zillig et al. Proc Natl Acad Sci U S A. 1975 Jul.

Abstract

After infection with bacteriophage T7 the beta' and to a lesser extent the beta subunits of E. coli DNA-dependent RNA polymerase (nucleosidetriphosphate:RNA nucleotidyltransferase, EC 2.7.7.6) are phosphorylated by a phage-gene-encoded protein kinase (ATP:protein phosphotransferase, EC 2.7.1.37). The phosphorylation occurs on threonine residues and appears site-specific. It is probably the molecular basis of the early transcriptional control.

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References

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