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. 1975 Aug 11;32(2):163-8.
doi: 10.1007/BF00689570.

Virus-like particles in Creutzfeldt-Jakob biopsy material

H K Narang

Virus-like particles in Creutzfeldt-Jakob biopsy material

H K Narang. Acta Neuropathol. .

Abstract

In an electron microscopic study of brain biopsy material from 6 patients with Creutzfeldt-Jacob disease, virus-like particles resembling herpes have been seen. These particles were found only in reactive astrocytes. In 2 out of 6 Creutzfeldt-Jacob brain biopsies some profiles were filled with tubular structures resembling the nucleocapsid of paramyxovirus. The findings are compared with other neurological conditions.

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