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. 2000 Mar 20;84(12):2754-7.
doi: 10.1103/PhysRevLett.84.2754.

Imaging sustained dissipative patterns in the metabolism of individual living cells

H R Petty  1 , R G Worth, A L Kindzelskii
Affiliations

Imaging sustained dissipative patterns in the metabolism of individual living cells

H R Petty et al. Phys Rev Lett. .

Abstract

Theoretical studies have predicted spatiotemporal organization of cell metabolism. Using a rapidly gated CCD camera, we demonstrate for the first time sustained traveling waves of NAD(P)H autofluorescence and protons in individual morphologically polarized living cells. Chemical concentration fronts moved in the direction of cell orientation, thus correlating dissipative structures with cell shape.

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