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Review
. 2000 Sep;2(11):1335-41.
doi: 10.1016/s1286-4579(00)01287-9.

Do infectious diseases drive MHC diversity?

K J Jeffery  1 , C R Bangham
Affiliations
Free article
Review

Do infectious diseases drive MHC diversity?

K J Jeffery et al. Microbes Infect. 2000 Sep.
Free article

Abstract

The primary function of the major histocompatibility complex (MHC) is to allow the immune system to identify infectious pathogens and eliminate them. Infectious diseases are now thought to be the main selection force that drives and maintains the extraordinary diversity of the MHC.

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