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Case Reports
. 2000 Sep;23(8):542-4.
doi: 10.1007/BF03343772.

Venous thrombo-embolism following inferior petrosal sinus sampling in Cushing's disease

K Obuobie  1 , J S Davies, A Ogunko, M F Scanlon
Affiliations
Case Reports

Venous thrombo-embolism following inferior petrosal sinus sampling in Cushing's disease

K Obuobie et al. J Endocrinol Invest. 2000 Sep.

Abstract

Bilateral inferior petrosal sinus sampling for ACTH with corticotrophin releasing hormone stimulation has become an established test in differentiating pituitary Cushing's disease from Cushing's syndrome due to ectopic ACTH secretion. We report two patients with Cushing's disease who developed thromboembolic complications soon after inferior petrosal sinus sampling. We discuss the possible mechanisms leading to this complication in a syndrome in which thromboembolic complications are well recognized and highlight the need for consideration of prophylactic anticoagulation.

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