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Review
. 2000 Sep;18(3):99-110.
doi: 10.1002/1099-1069(200009)18:3<99::aid-hon662>3.0.co;2-z.

DNA repair mechanisms and acute myeloblastic leukemia

E P Das-Gupta  1 , C H Seedhouse, N H Russell
Affiliations
Review

DNA repair mechanisms and acute myeloblastic leukemia

E P Das-Gupta et al. Hematol Oncol. 2000 Sep.

Abstract

DNA repair mechanisms play a vital role in maintaining genomic integrity. With the wealth of knowledge gained recently on these processes it is becoming clear that defects in repair proteins and proteins associated with the regulation of repair are connected to many different human diseases including cancer. This paper has aimed to review the four major DNA repair processes and in particular concentrate on their association with acute myeloblastic leukemia (AML).

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