Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1975 Jun 19;138(3):225-32.
doi: 10.1007/BF00269349.

Isolation and characterization of mutants with a feedback resistant N-acetylglutamate synthase in Escherichia coli K 12

T Eckhardt, T Leisinger

Isolation and characterization of mutants with a feedback resistant N-acetylglutamate synthase in Escherichia coli K 12

T Eckhardt et al. Mol Gen Genet. .

Abstract

Mutants with a feedback resistant N-acetylglutamate synthase have been isolated from a proA/B, argD, argR strain by screening for proline excretion on minimal medium with arginine. The feedback resistant character of three mutants was transduced into an argA (N-acetylglutamate synthase negative) strain. It was cotransducible with argA at a frequency of greater than 99%. N-acetylglutamate synthase extracted from the three mutants was approximately one hundred times less sensitive to L-arginine than the enzyme from the feedback sensitive parent strain.

PubMed Disclaimer

References

    1. Mol Gen Genet. 1970;106(2):162-73 - PubMed
    1. Bacteriol Rev. 1970 Jun;34(2):155-75 - PubMed
    1. Pathol Microbiol (Basel). 1974;40(3):140-1 - PubMed
    1. J Bacteriol. 1950 Jul;60(1):17-28 - PubMed
    1. J Bacteriol. 1965 Aug;90:554-5 - PubMed

LinkOut - more resources