DBP exerts its antiandrogenic activity by indirectly interfering with androgen signaling pathways

Comment

E Mylchreest et al. Toxicol Appl Pharmacol. 2000.

. 2000 Oct 15;168(2):174-5.

doi: 10.1006/taap.2000.9031.

No abstract available

Comment on

Disruption of androgen-regulated male reproductive development by di(n-butyl) phthalate during late gestation in rats is different from flutamide.
Mylchreest E, Sar M, Cattley RC, Foster PM. Mylchreest E, et al. Toxicol Appl Pharmacol. 1999 Apr 15;156(2):81-95. doi: 10.1006/taap.1999.8643. Toxicol Appl Pharmacol. 1999. PMID: 10198273
Reasonable explanation for both the antiandrogenic mechanism of DBP and DBP-induced Leydig cell hyperplasia in prenatally DBP-treated rats.
Shono T, Suita S. Shono T, et al. Toxicol Appl Pharmacol. 2000 May 1;164(3):336. doi: 10.1006/taap.1999.8867. Toxicol Appl Pharmacol. 2000. PMID: 10799345 No abstract available.