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. 2000 Nov;67(5):1356-9.
doi: 10.1016/S0002-9297(07)62969-3.

The promise and pitfalls of telomere region-specific probes

B C Ballif, C D Kashork, L G Shaffer

The promise and pitfalls of telomere region-specific probes

B C Ballif et al. Am J Hum Genet. 2000 Nov.
No abstract available

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Figures

Figure 1
Figure 1
Subtelomeric polymorphisms detected by telomere region–specific FISH probes. Probes specific for p arms fluoresce green, and probes specific for q arms fluoresce red. A, Metaphase from a phenotypically normal parent, showing a deletion of the 2q telomere region–specific FISH probe (arrow). Note a normal hybridization pattern for the 2p telomere region–specific FISH probe. B, Metaphase from the child of the parent shown in A, indicating an inherited deletion of the 2q FISH probe (arrow). C, Metaphase from a patient with a polymorphic deletion of the Xp subtelomeric probe (arrow) that was paternally inherited (parental data not shown). D, Metaphase from a patient showing a polymorphic deletion, of the 9p FISH probe (arrow), that was paternally inherited (parental data not shown).
See this image and copyright information in PMC

References

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