The influence of parity and gravidity on first trimester markers of chromosomal abnormality
Affiliations
- PMID: 11038455
Item in Clipboard
The influence of parity and gravidity on first trimester markers of chromosomal abnormality
Prenat Diagn.
2000 Oct.
Abstract
We have studied changes in first trimester fetal nuchal translucency (NT) and maternal serum free beta-hCG and PAPP-A with gravidity and parity in 3252 singleton pregnancies unaffected by chromosomal abnormality or major pregnancy complications. We have shown that gravidity and parity is associated with a small but progressive decrease in fetal NT and a small but progressive increase in free beta-hCG and PAPP-A. None of these small changes with increasing gravidity or parity are statistically significant and hence correction for these variables is not necessary when considering first trimester screening for chromosomal abnormalities.
Copyright 2000 John Wiley & Sons, Ltd.
Similar articles
-
Maternal serum free-beta-chorionic gonadotrophin, pregnancy-associated plasma protein-A and fetal nuchal translucency thickness at 10-13(+6) weeks in relation to co-variables in pregnant Saudi women.Prenat Diagn. 2007 Apr;27(4):303-11. doi: 10.1002/pd.1661. Prenat Diagn. 2007. PMID: 17269128
-
The impact of correcting for smoking status when screening for chromosomal anomalies using maternal serum biochemistry and fetal nuchal translucency thickness in the first trimester of pregnancy.Prenat Diagn. 2004 Mar;24(3):169-73. doi: 10.1002/pd.819. Prenat Diagn. 2004. PMID: 15057947
-
Screening for trisomy 21 by fetal tricuspid regurgitation, nuchal translucency and maternal serum free beta-hCG and PAPP-A at 11 + 0 to 13 + 6 weeks.Ultrasound Obstet Gynecol. 2006 Feb;27(2):151-5. doi: 10.1002/uog.2699. Ultrasound Obstet Gynecol. 2006. PMID: 16388509
-
First-trimester ultrasound and biochemical markers of aneuploidy and the prediction of impending fetal death.Ultrasound Obstet Gynecol. 2006 Oct;28(5):637-43. doi: 10.1002/uog.3809. Ultrasound Obstet Gynecol. 2006. PMID: 16952214 Review.
-
[Trisomy 21 screening: value of ultrasound and serum markers in a combined approach].J Gynecol Obstet Biol Reprod (Paris). 2001 Feb;30(1):11-27. J Gynecol Obstet Biol Reprod (Paris). 2001. PMID: 11240502 Review. French. No abstract available.
Cited by
-
Urine tests for Down's syndrome screening.Cochrane Database Syst Rev. 2015 Dec 10;2015(12):CD011984. doi: 10.1002/14651858.CD011984. Cochrane Database Syst Rev. 2015. PMID: 26662198 Free PMC article.
-
First trimester serum tests for Down's syndrome screening.Cochrane Database Syst Rev. 2015 Nov 30;2015(11):CD011975. doi: 10.1002/14651858.CD011975. Cochrane Database Syst Rev. 2015. PMID: 26617074 Free PMC article.
-
First and second trimester serum tests with and without first trimester ultrasound tests for Down's syndrome screening.Cochrane Database Syst Rev. 2017 Mar 15;3(3):CD012599. doi: 10.1002/14651858.CD012599. Cochrane Database Syst Rev. 2017. PMID: 28295159 Free PMC article.
-
Association between pregnancy and pregnancy loss with COPD in Chinese women: The China Kadoorie Biobank study.Front Public Health. 2022 Oct 31;10:990057. doi: 10.3389/fpubh.2022.990057. eCollection 2022. Front Public Health. 2022. PMID: 36388344 Free PMC article.
-
First trimester ultrasound tests alone or in combination with first trimester serum tests for Down's syndrome screening.Cochrane Database Syst Rev. 2017 Mar 15;3(3):CD012600. doi: 10.1002/14651858.CD012600. Cochrane Database Syst Rev. 2017. PMID: 28295158 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Research Materials
Miscellaneous
