A technique for intensifying BCG sensitivity
- PMID: 1104733
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A technique for intensifying BCG sensitivity
J Med.
1975.
Abstract
Sensitization to BCG (Bacille Calmette-Guérin) appears to be more effective when it is carried out at the site of a delayed hypersensitivity challenge reaction to DNCB (1-chloro, 2,4-dinitrobenzene) than when it is carried out at unchallenged sites in non-sensitized animals. The effectiveness of BCG sensitization was determined by measurement of the intensity of the PPD (Purified Protein Derivative of tuberculin) 24-hour skin test. Possible mechanisms for this phenomenon and its implications for cancer immunotherapy are considered.
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