Review
doi: 10.1016/s0167-7799(00)01499-2.
Frontiers in chemical genetics
Affiliations
- PMID: 11058785
- DOI: 10.1016/s0167-7799(00)01499-2
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Review
Frontiers in chemical genetics
Trends Biotechnol.
2000 Nov.
Abstract
New methods enable the identification of compounds that both induce a specific cellular state and lead to identification of proteins that regulate that state. Together, developments in three critical areas: chemical diversity, phenotype-based screening and target identification, enable the systematic application of this chemical genetic approach to almost any biological problem or disease process.
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