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Review
. 2000 Nov;18(11):449-55.
doi: 10.1016/s0167-7799(00)01499-2.

Frontiers in chemical genetics

B R Stockwell  1
Affiliations
Review

Frontiers in chemical genetics

B R Stockwell. Trends Biotechnol. 2000 Nov.

Abstract

New methods enable the identification of compounds that both induce a specific cellular state and lead to identification of proteins that regulate that state. Together, developments in three critical areas: chemical diversity, phenotype-based screening and target identification, enable the systematic application of this chemical genetic approach to almost any biological problem or disease process.

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