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Review
. 2000;4(6):488-98.
doi: 10.1007/s11916-000-0073-8.

Calcium channel blockers and pain therapy

B Cox  1
Affiliations
Review

Calcium channel blockers and pain therapy

B Cox. Curr Rev Pain. 2000.

Abstract

This review focuses on the advances in the development of N-type calcium channel blockers as analgesic agents over the last 2 years. Firstly, it highlights the clinical progress with SNX-111 (Ziconotide; Elan Pharmaceuticals, Smithfield, RI) and then secondly, it outlines the various approaches being taken by researchers to design orally active, selective, small molecule modulators without the perceived disadvantages associated with SNX-111.

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