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. 2000 Nov;26(3):267-8.
doi: 10.1038/81547.

Mater, a maternal effect gene required for early embryonic development in mice

Z B Tong  1 , L Gold, K E Pfeifer, H Dorward, E Lee, C A Bondy, J Dean, L M Nelson
Affiliations

Mater, a maternal effect gene required for early embryonic development in mice

Z B Tong et al. Nat Genet. 2000 Nov.

Abstract

Maternal effect genes produce mRNA or proteins that accumulate in the egg during oogenesis. We show here that Mater, a mouse oocyte protein dependent on the maternal genome, is essential for embryonic development beyond the two-cell stage. Females lacking the maternal effect gene Mater are sterile. Null males are fertile.

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