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Comparative Study
. 2000 Nov;39(11):1432-7.
doi: 10.1097/00004583-200011000-00018.

Adoptive and biological families of children and adolescents with ADHD

S Sprich  1 , J Biederman, M H Crawford, E Mundy, S V Faraone
Affiliations
Comparative Study

Adoptive and biological families of children and adolescents with ADHD

S Sprich et al. J Am Acad Child Adolesc Psychiatry. 2000 Nov.

Abstract

Objective: Using an adoption study design, the authors addressed the issue of genetics in attention-deficit hyperactivity disorder (ADHD).

Method: This study examined the rates of ADHD and associated disorders in the first-degree adoptive relatives of 25 adopted probands with ADHD and compared them with those of the first-degree biological relatives of 101 nonadopted probands with ADHD and 50 nonadopted, non-ADHD control probands.

Results: Six percent of the adoptive parents of adopted ADHD probands had ADHD compared with 18% of the biological parents of nonadopted ADHD probands and 3% of the biological parents of the control probands.

Conclusion: Results of this study lend support to the hypothesis that ADHD has a genetic component.

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Comment in

  • Adoption study of ADHD.
    Joseph J. Joseph J. J Am Acad Child Adolesc Psychiatry. 2002 Dec;41(12):1389-90; author reply 1390-1. doi: 10.1097/00004583-200212000-00002. J Am Acad Child Adolesc Psychiatry. 2002. PMID: 12447020 No abstract available.

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