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Comparative Study
. 2000 Nov 1;48(4):1241-4.
doi: 10.1016/s0360-3016(00)00734-3.

Dosimetric comparison of pre-planned and or-planned prostate seed brachytherapy

D A Wilkinson  1 , E J Lee, J P Ciezki, D S Mohan, C Zippe, K Angermeier, J Ulchaker, E A Klein
Affiliations
Comparative Study

Dosimetric comparison of pre-planned and or-planned prostate seed brachytherapy

D A Wilkinson et al. Int J Radiat Oncol Biol Phys. .

Erratum in

  • Int J Radiat Oncol Biol Phys 2001 Jan 1;49(1):297. Mohan D [corrected to Mohan DS]

Abstract

Purpose: To compare the dosimetry of the traditional two step procedure (volume study + treatment planning several weeks later) with that of an OR-based single procedure in which these two steps follow one another immediately. Computer generated treatment plans were used in both procedures.

Methods and materials: Several dosimetric parameters relating to target coverage were obtained from dose volume histograms of CT-based evaluation plans developed either 1 or 3 days following seed implantation. A total of 113 patients with early stage (T1C, T2A) prostate cancer were used for this retrospective study.

Results: The fraction of target (prostate) covered by the prescription dose (144 Gy), 90% of the prescription dose (115 Gy), and the dose encompassing 90% of the target in the evaluation plan were all statistically significantly improved for OR-based plans compared to pre-planned cases.

Conclusion: In our hands, there is a small but significant improvement in dose coverage of the prostate when the ultrasound volume study and treatment planning are combined into a single procedure.

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