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. 2000 Oct 7;356(9237):1244-5.
doi: 10.1016/S0140-6736(00)02795-1.

Melatonin secretion after surgery

A J Cronin, J C Keifer, M F Davies, T S King, E O Bixler

Melatonin secretion after surgery

A J Cronin et al. Lancet. .

Abstract

Sleep disturbance is common postoperatively. We examined whether melatonin concentrations were related to this disturbance in seven postoperative patients. Nocturnal concentrations of melatonin were significantly (p=0.005) lower on the first than on the second or third nights after surgery. This finding raises the possibility that melatonin suppression and associated sleep disturbance might be prevented by melatonin replacement.

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  • Melatonin secretion after surgery.
    Srinivasan V. Srinivasan V. Lancet. 2001 Feb 17;357(9255):557-8. doi: 10.1016/S0140-6736(05)71706-2. Lancet. 2001. PMID: 11229697 No abstract available.