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Comparative Study
. 1976 Jan;125(1):149-57.
doi: 10.1128/jb.125.1.149-157.1976.

Plasmid-determined beta-lactamase indistinguishable from the chromosomal beta-lactamase of Escherichia coli

M M Bobrowski, M Matthew, P T Barth, N Datta, N J Grinter, A E Jacob, P Kontomichalou, J W Dale, J T Smith
Comparative Study

Plasmid-determined beta-lactamase indistinguishable from the chromosomal beta-lactamase of Escherichia coli

M M Bobrowski et al. J Bacteriol. 1976 Jan.

Abstract

A plasmid, derived from a naturally occurring strain of Proteus mirabilis, conferred resistance to cephalosporins, apparently mediated by a beta-lactamase indistinguishable from that determined by the chromosomal gene of Escherichia coli K-12. There was evidence for a recombination event between the wild-type plasmid and a defective F factor (Fsp) in the Escherichia coli K-12 culture in which it was stored.

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References

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